상세 보기
- Baiseitova, Aizhamal;
- Amzeyeva, Ulpan;
- Tolepbergen, Aiya;
- Ulfanova, Yasmina;
- Shybyray, Yergazy;
- ... Kim, Jeong Yoon;
- 외 4명
WEB OF SCIENCE
1SCOPUS
1초록
Chicory (Cichorium intybus L.) roots are commonly roasted and ground to produce a coffee alternative, valued for its robust, nutty taste and absence of caffeine. Historically, it has been utilized to facilitate digestion, serve as a diuretic, and promote liver function. This study employed a response surface methodology (RSM) for optimization the ultrasonic-assisted extraction of antioxidant composition from chicory. The optimal extraction conditions (temperature 60 degrees C, extraction duration 4 h, and solid-to-solvent ratio of 1:20 g/mL) resulted in the maximum yield and antioxidant capacity. The metabolic content of chicory extract, prepared under optimal conditions, was found by UPLC-ESI-QTOF/MS, including aesculetin, caftaric acid, caffeoylmalic acid, scopoletin, and chicoric acid. Moreover, chicory extracts derived under identical conditions in two distinct solvents (96% and 50% ethanol) demonstrated vitality and hepatoprotective action in HL-7702 cells. This study may offer a perspective for acquiring potential extracts of chicory as a functional food.
키워드
- 제목
- Response Surface Methodology Optimization on Ultrasonic-Assisted Extraction of Chicory (Cichorium intybus L.) and Their UPLC-ESI-QTOF-MS Analysis, Antioxidant and Hepatoprotective Activity
- 저자
- Baiseitova, Aizhamal; Amzeyeva, Ulpan; Tolepbergen, Aiya; Ulfanova, Yasmina; Shybyray, Yergazy; Dai, Lixia; Shang, Xiaofei; Shah, Abdul Bari; Kim, Jeong Yoon; Jenis, Janar
- 발행일
- 2025-06
- 유형
- Article
- 저널명
- eFood
- 권
- 6
- 호
- 4