상세 보기
- Kim, Min Jung;
- Jang, Mi Jin;
- Yang, Ju-Hye;
- You, Young Zoo;
- Yang, Ye Jin;
- ... Park, Kwang Il;
- 외 4명
WEB OF SCIENCE
0SCOPUS
0초록
Background Oxidative stress and lipid peroxidation play crucial roles in the pathogenesis of atopic dermatitis (AD). Among the by-products of lipid peroxidation, 4-hydroxynonenal (4-HNE) is known to exacerbate inflammatory responses.Methods This study investigated the potential of Cinnamomum verum J. Presl. [Lauraceae] extract (CVE) in mitigating oxidative stress and suppressing 4-HNE-mediated inflammatory pathways in an AD model. The antioxidant properties of CVE were evaluated through lipid peroxidation assays, reactive oxygen species (ROS) measurement, and cytokine profiling.Results CVE treatment significantly reduced 4-HNE levels, decreased pro-inflammatory cytokine expression, and restored antioxidant enzyme activity.Conclusion These findings suggest that CVE may serve as a natural therapeutic agent for managing oxidative stress and inflammation in AD.
키워드
- 제목
- Cinnamomum verum extract as a potential therapeutic for atopic dermatitis through reducing lipid peroxidation and oxidative stress
- 저자
- Kim, Min Jung; Jang, Mi Jin; Yang, Ju-Hye; You, Young Zoo; Yang, Ye Jin; Heo, Ji Woong; Choi, Han Nim; Jeon, Ryounghoon; An, Sang-Hyun; Park, Kwang Il
- 발행일
- 2026-01
- 유형
- Article
- 권
- 16