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초록
Cooperative Rh(II) and Pd(0) dual relay catalysis has been developed, which allowed one-pot synthesis of alpha-quaternary allylated indolin-2-ones and benzofuran-2-ones. The catalytic reaction proceeded through the sequential Rh(II)-catalyzed intramolecular aromatic C(sp(2))-H bond functionalization of alpha-diazo carbonyl compounds, followed by Pd(0)-catalyzed allylic alkylation with allylic carbonates to afford the products in high yields (up to 97%).
키워드
Dual catalysis; Rhodium catalyst; Palladium catalyst; Indolin‐ 2‐ ones; Benzofuran‐ 2‐ ones; DECARBOXYLATIVE ALLYLIC ALKYLATION; C-H FUNCTIONALIZATION; ENANTIOSELECTIVE CONSTRUCTION; BIMETALLIC CATALYSIS; ASYMMETRIC-SYNTHESIS; TRANSITION; PALLADIUM; ESTERS; DERIVATIVES; AMINATION
- 제목
- Dual Rh(II)/Pd(0) Relay Catalysis for One-Pot Synthesis of α-Quaternary Allylated Indolin-2-ones and Benzofuran-2-ones
- 저자
- Lee, Yu Lim; Lee, Kyu Ree; Xuan, Zi; Lee, Sang-gi
- 발행일
- 2021-03
- 유형
- Article
- 권
- 42
- 호
- 3
- 페이지
- 537 ~ 541