Recent Updates on Source, Biosynthesis, and Therapeutic Potential of Natural Flavonoid Luteolin: A Review
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초록

Nature gives immense resources that are beneficial to humankind. The natural compounds present in plants provide primary nutritional values to our diet. Apart from food, plants also provide chemical compounds with therapeutic values. The importance of these plant secondary metabolites is increasing due to more studies revealing their beneficial properties in treating and managing various diseases and their symptoms. Among them, flavonoids are crucial secondary metabolite compounds present in most plants. Of the reported 8000 flavonoid compounds, luteolin is an essential dietary compound. This review discusses the source of the essential flavonoid luteolin in various plants and its biosynthesis. Furthermore, the potential health benefits of luteolins such as anti-cancer, anti-microbial, anti-inflammatory, antioxidant, and anti-diabetic effects and their mechanisms are discussed in detail. The activity of luteolin and its derivatives are diverse, as they help to prevent and control many diseases and their life-threatening effects. This review will enhance the knowledge and recent findings regarding luteolin and its therapeutic effects, which are certainly useful in potentially utilizing this natural metabolite.

키워드

anti-inflammatoryanti-canceranti-diabeticluteolinsecondary metaboliteflavonoidDIETARY FLAVONOIDSDNA-DAMAGEIN-VITROAPOPTOSISANTIOXIDANTQUERCETINCONSTITUENTSSUPPRESSIONPROLIFERATIONCOMBINATION
제목
Recent Updates on Source, Biosynthesis, and Therapeutic Potential of Natural Flavonoid Luteolin: A Review
저자
Muruganathan, NandakumarDhanapal, Anand RajBaskar, VenkidasamyMuthuramalingam, PandiyanSelvaraj, DhivyaAara, HusneAbdullah, Mohamed Zubair ShiekSivanesan, Iyyakkannu
DOI
10.3390/metabo12111145
발행일
2022-11
유형
Review
저널명
Metabolites
12
11