Development of Advanced Macrosphelides: Potent Anticancer Agents

Paek, Seung-Mann

doi:10.3390/molecules20034430

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Development of Advanced Macrosphelides: Potent Anticancer Agents

Paek, Seung-Mann

Citations

WEB OF SCIENCE

7

Citations

SCOPUS

7

초록

Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography preparation. In addition, advances in their apoptosis-inducing activities are also included.

키워드

Analogs; Macrosphelides; Medicinal chemistry; ORALLY BIOAVAILABLE INHIBITORS; ABSOLUTE STEREOCHEMISTRIES; ARTIFICIAL MACROSPHELIDES; SIDE-CHAIN; APOPTOSIS; (+)-MACROSPHELIDE-A; METASTASIS; STRATEGY; LIBRARY; ANALOGS

제목: Development of Advanced Macrosphelides: Potent Anticancer Agents

저자: Paek, Seung-Mann

DOI: 10.3390/molecules20034430

발행일: 2015-03

유형: Review

저널명: Molecules

권: 20

호: 3

페이지: 4430 ~ 4449

언어: ENG

출판사: MDPI

발행국가: 스위스

분량: 20 페이지

ISSN: E 1420-3049
P 1420-3049