Host Subcellular Organelles: Targets of Viral Manipulation
Citations

WEB OF SCIENCE

8
Citations

SCOPUS

9

초록

Viruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular machinery and impair homeostasis. Moreover, viral infection alters the cell membrane’s structure and composition and induces vesicle formation to facilitate intracellular trafficking of viral components. However, the research focus has predominantly been on the immune response elicited by viruses, often overlooking the significant alterations that viruses induce in cellular organelles. Gaining a deeper understanding of these virus-induced cellular changes is crucial for elucidating the full life cycle of viruses and developing potent antiviral therapies. Exploring virus-induced cellular changes could substantially improve our understanding of viral infection mechanisms. © 2024 by the authors.

키워드

endocytosisendoplasmic reticuluminfectionlysosomemembraneorganellesvirusENDOPLASMIC-RETICULUMVIRUS-REPLICATIONMITOCHONDRIAL FISSIONEXTRACELLULAR-MATRIXULTRASTRUCTURAL CHARACTERIZATIONRECEPTOR SPECIFICITYMEMBRANE-VESICLESNUCLEAR IMPORTCELL ENTRYPROTEIN
제목
Host Subcellular Organelles: Targets of Viral Manipulation
저자
Song, Min SeokLee, Dong-KunLee, Chung-YoungPark, Sang-CheolYang, Jinsung
DOI
10.3390/ijms25031638
발행일
2024-02
유형
Review
저널명
International Journal of Molecular Sciences
25
3