Molecular characterization and gene expression data of liver expressed antimicrobial Peptide-2 (LEAP-2) isolated from rock bream (Oplegnathus fasciatus)

  • Hwang, Seong Don; 
  • Joo, Min Soo; 
  • Hwang, Jee Youn; 
  • Kwon, Mun-Gyeong; 
  • Jeong, Ji-Min; 
  • ... Park, Chan-Il; 
  • 외 2명
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8

초록

Antimicrobial peptides (AMPs) are known to play a role as a first line of defence against microbial invasion. Liver Expressed Antimicrobial Peptides-2 (LEAP-2) is one of the AMPs. LEAP-2 includes four highly conserved cysteine residues and belongs to a cysteine-rich peptides group. We identified and characterized the molecular properties of LEAP-2 in rock bream. The expression levels of rock bream LEAP-2 (RbLEAP-2) in the 12 different tissues of healthy fish and the RbLEAP-2 expression pattern after infections with Edwardsiella piscicida (E. piscicida), Streptococcus iniae (S. iniae) and red seabream iridovirus (RSIV) were examined. This data provide that RbLEAP-2 plays an important role in innate immunity when rock bream is infected with a pathogen. (c) 2019 The Author(s). Published by Elsevier Inc.

키워드

Rock bream; Liver expressed antimicrobial Peptide-2; Innate immune system; Antimicrobial peptides; Antimicrobial activity
제목
Molecular characterization and gene expression data of liver expressed antimicrobial Peptide-2 (LEAP-2) isolated from rock bream (Oplegnathus fasciatus)
저자
Hwang, Seong Don; Joo, Min Soo; Hwang, Jee Youn; Kwon, Mun-Gyeong; Jeong, Ji-Min; Seo, Jung Soo; Jee, Bo-Yeong; Park, Chan-Il
DOI
10.1016/j.dib.2019.104538
발행일
2019-10
유형
Article; Data Paper
저널명
Data in Brief
권
26