상세 보기
Molecular characterization and gene expression data of liver expressed antimicrobial Peptide-2 (LEAP-2) isolated from rock bream (Oplegnathus fasciatus)
- Hwang, Seong Don;
- Joo, Min Soo;
- Hwang, Jee Youn;
- Kwon, Mun-Gyeong;
- Jeong, Ji-Min;
- ... Park, Chan-Il;
- 외 2명
WEB OF SCIENCE
7SCOPUS
8초록
Antimicrobial peptides (AMPs) are known to play a role as a first line of defence against microbial invasion. Liver Expressed Antimicrobial Peptides-2 (LEAP-2) is one of the AMPs. LEAP-2 includes four highly conserved cysteine residues and belongs to a cysteine-rich peptides group. We identified and characterized the molecular properties of LEAP-2 in rock bream. The expression levels of rock bream LEAP-2 (RbLEAP-2) in the 12 different tissues of healthy fish and the RbLEAP-2 expression pattern after infections with Edwardsiella piscicida (E. piscicida), Streptococcus iniae (S. iniae) and red seabream iridovirus (RSIV) were examined. This data provide that RbLEAP-2 plays an important role in innate immunity when rock bream is infected with a pathogen. (c) 2019 The Author(s). Published by Elsevier Inc.
키워드
- 제목
- Molecular characterization and gene expression data of liver expressed antimicrobial Peptide-2 (LEAP-2) isolated from rock bream (Oplegnathus fasciatus)
- 저자
- Hwang, Seong Don; Joo, Min Soo; Hwang, Jee Youn; Kwon, Mun-Gyeong; Jeong, Ji-Min; Seo, Jung Soo; Jee, Bo-Yeong; Park, Chan-Il
- 발행일
- 2019-10
- 유형
- Article; Data Paper
- 저널명
- Data in Brief
- 권
- 26