이소니아지드와 리팜핀 복합 치료에 의하여 발생한속섬유막뒤다리의 양측성 병변

Bilateral Lesions in the Posterior Limb of Internal Capsule Attributed to Combination Therapy of Isoniazid and Rifampin
  • 박민원; 
  • 노진홍; 
  • 임서준; 
  • 김민옥; 
  • 김영수; 
  • ... 권오영; 
  • 외 1명

초록

Transient isoniazid-induced brain lesions have rarely been reported. The lesions were in the dentate nucleus of cerebellum and thalamus. Meanwhile, the neurotoxicity of rifampin has not been reported evidently. We observed bilateral lesions in the internal capsule in a young woman after taking a combination of isoniazid and rifampin. She transiently suffered numbness in both hands, dysarthria, and left side motor weakness while taking the medication. Isoniazid may induce structural lesions in various brain areas including the internal capsule.

키워드

Isoniazid; Neurotoxicity syndromes; Internal capsule
제목
이소니아지드와 리팜핀 복합 치료에 의하여 발생한속섬유막뒤다리의 양측성 병변
제목 (타언어)
Bilateral Lesions in the Posterior Limb of Internal Capsule Attributed to Combination Therapy of Isoniazid and Rifampin
저자
박민원; 노진홍; 임서준; 김민옥; 김영수; 김도형; 권오영
DOI
10.17340/jkna.2018.4.17
발행일
2018
저널명
대한신경과학회지
권
36
호
4
페이지
345 ~ 357