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Surgical treatment of medication-related osteonecrosis of the jaw in patients with autoimmune diseasesopen accessSurgical treatment of medication-related osteonecrosis of the jaw in patients with autoimmune diseases
- Other Titles
- Surgical treatment of medication-related osteonecrosis of the jaw in patients with autoimmune diseases
- Authors
- Young Hoon Kang; Na Young Lee
- Issue Date
- Jun-2024
- Publisher
- 조선대학교 치의학연구원
- Keywords
- Autoimmune diseases; Bisphosphonate; Osteoporosis; Surgical treatment
- Citation
- Oral Biology Research, v.48, no.2, pp 45 - 51
- Pages
- 7
- Indexed
- KCI
- Journal Title
- Oral Biology Research
- Volume
- 48
- Number
- 2
- Start Page
- 45
- End Page
- 51
- ISSN
- 2508-2558
2508-2566
- Abstract
- This retrospective, single-center study compares the factors influencing the surgical outcomes of medication-related osteonecrosis of the jaw (MRONJ) in patients with and without autoimmune diseases (AIDs). The total surgical success rate was 92% during the mean 2-year follow-up period, and treatment failure was observed in 8% of all patients without AID and 12% of patients with AIDs. Bisphosphonate duration and administration route (intravenous) were found to be risk factors of MRONJ. A careful treatment plan should be developed with a multidisciplinary team including a rheumatologist and a maxillofacial surgeon to avoid the use of drugs that may adversely affect treatment results when MRONJ occurs in patients with AIDs.
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