Detailed Information

Cited 6 time in webofscience Cited 8 time in scopus
Metadata Downloads

Transcatheter arterial embolization for gastrointestinal bleeding related to pancreatic adenocarcinoma: clinical efficacy and predictors of clinical outcome

Authors
Lee, Sang MinJeong, So YeongShin, Ji HoonChoi, Ho CheolNa, Jae BoemWon, Jung HoPark, Sung EunChen, Cheng Shi
Issue Date
Feb-2020
Publisher
Elsevier BV
Keywords
Pancreatic cancer; Gastrointestinal bleeding; Endovascular embolization
Citation
European Journal of Radiology, v.123
Indexed
SCIE
SCOPUS
Journal Title
European Journal of Radiology
Volume
123
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/6976
DOI
10.1016/j.ejrad.2019.108787
ISSN
0720-048X
1872-7727
Abstract
Purpose: To evaluate the clinical efficacy of transcatheter arterial embolization (TAE) for managing pancreatic adenocarcinoma-related gastrointestinal (GI) bleeding, and to determine the factors associated with clinical outcomes. Method: From 2001-2017, this retrospective study included 58 patients who underwent TAE for pancreatic adenocarcinoma-related GI bleeding. The technical and clinical success of TAE, clinical factors including patient characteristics and embolization details, complications, and the 30-day mortality were evaluated. Univariate analyses were performed to determine the factors related to the clinical outcomes. Results: On angiography, bleeding foci were detected in 47 patients (81%), while the other 11 patients showed tumor staining. Technical success rate was 98%, and first session and overall clinical success rates were 79% and 88%, respectively. N-butyl cyanoacrylate (NBCA) was the most commonly used embolic agent (53%). Stent-related bleeding was shown in 22 patients with characteristic angiogram such as arterial cut-off (13/22) and arteriobiliary fistula (5/22), with comparable clinical success rate (82%). Bleeding from the superior mesenteric artery (n = 3) at the first session of angiography and complications (n = 2), such as ischemic hepatitis and small bowel infarction, were all associated with a 30-day mortality. The overall 30-day mortality rate was 22%. Univariate analysis showed that massive transfusion and TNM stage 4 were related to clinical failure (P = 0.035 and 0.038, respectively). Conclusions: TAE was effective and safe for pancreatic adenocarcinoma-related GI bleeding. Scent-related bleeding was not uncommon, and associated with vascular abnormality amenable to TAE. Massive transfusion and TNM stage 4 were related to clinical failure.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medicine > Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Na, Jae Boem photo

Na, Jae Boem
의과대학 (의학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE