Detailed Information

Cited 11 time in webofscience Cited 15 time in scopus
Metadata Downloads

Rapid Muscle Loss Negatively Impacts Survival in Critically Ill Patients With Cirrhosis

Full metadata record
DC Field Value Language
dc.contributor.authorJu, Sunmi-
dc.contributor.authorChoi, Sun Mi-
dc.contributor.authorPark, Young Sik-
dc.contributor.authorLee, Chang-Hoon-
dc.contributor.authorLee, Sang-Min-
dc.contributor.authorYoo, Chul-Gyu-
dc.contributor.authorKim, Young Whan-
dc.contributor.authorHan, Sung Koo-
dc.contributor.authorLee, Jinwoo-
dc.date.accessioned2022-12-26T12:33:09Z-
dc.date.available2022-12-26T12:33:09Z-
dc.date.issued2020-07-
dc.identifier.issn0885-0666-
dc.identifier.issn1525-1489-
dc.identifier.urihttps://scholarworks.gnu.ac.kr/handle/sw.gnu/6432-
dc.description.abstractPurpose: To assess the impact of rapid muscle loss before admission to intensive care unit (ICU) in critically ill patients with cirrhosis. Materials and Methods: Patients with cirrhosis who had undergone 2 or more recent computed tomography scans before admission to the medical ICU were included. Muscle cross-sectional area at the level of the third lumbar vertebra was quantified using OsiriX software. The rate of muscle mass change and skeletal muscle index (SMI) were also calculated. Multivariable Cox proportional hazards regression was used to evaluate the association between muscle loss and mortality. Results: Among 125 patients, 113 (90.4%) patients were classified as having sarcopenia. The mean body mass index was 22.6 (3.9) kg/m(2). Thirty-nine (31.2%) patients were within the normal range for muscle mass change, while 86 (68.8%) patients demonstrated rapid decline in muscle mass before admission to the ICU. Patients with rapid muscle loss showed high ICU mortality (59.3%) and in-hospital mortality (77.9%). Multivariate Cox analysis showed that ICU mortality and in-hospital mortality were independently associated with malignancy, Acute Physiology and Chronic Health Evaluation (APACHE) II score, SMI, and rapid muscle loss. Conclusion: Rapid muscle decline is correlated with increased ICU mortality and in-hospital mortality in critically ill patients with cirrhosis.-
dc.format.extent9-
dc.language영어-
dc.language.isoENG-
dc.publisherSAGE Publications-
dc.titleRapid Muscle Loss Negatively Impacts Survival in Critically Ill Patients With Cirrhosis-
dc.typeArticle-
dc.publisher.location미국-
dc.identifier.doi10.1177/0885066618775706-
dc.identifier.scopusid2-s2.0-85085694751-
dc.identifier.wosid000537178500007-
dc.identifier.bibliographicCitationJournal of Intensive Care Medicine, v.35, no.7, pp 663 - 671-
dc.citation.titleJournal of Intensive Care Medicine-
dc.citation.volume35-
dc.citation.number7-
dc.citation.startPage663-
dc.citation.endPage671-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaGeneral & Internal Medicine-
dc.relation.journalWebOfScienceCategoryCritical Care Medicine-
dc.subject.keywordPlusSTAGE LIVER-DISEASE-
dc.subject.keywordPlusSKELETAL-MUSCLE-
dc.subject.keywordPlusBODY-COMPOSITION-
dc.subject.keywordPlusCOMPUTED-TOMOGRAPHY-
dc.subject.keywordPlusSARCOPENIC OBESITY-
dc.subject.keywordPlusSOLID TUMORS-
dc.subject.keywordPlusMASS-
dc.subject.keywordPlusPREVALENCE-
dc.subject.keywordPlusAGE-
dc.subject.keywordPlusMORTALITY-
dc.subject.keywordAuthormuscles-
dc.subject.keywordAuthorsarcopenia-
dc.subject.keywordAuthorliver cirrhosis-
dc.subject.keywordAuthorintensive care unit-
dc.subject.keywordAuthormortality-
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medicine > Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Ju, Sun Mi photo

Ju, Sun Mi
의과대학 (의학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE