참돔(Pagrus major)에서 동정된 Lumican의 분자적 특성과 유전자 발현분석

Abstract

Lumican is a member of the small leucine-rich proteoglycan (SLRP) proteoglycan Class II family. In particular, it plays the role of a regulator of extracellular matrix (ECM) tissue and biological function. It also has a function for tissue repair by regulating collagen fibrin formation in interstitial tissue. In this study, after analyzing the characteristics and expression of lumican in red sea bream, the highest expression was found in the skin, and expression was also confirmed after infection with Edwardsiella piscicida (E. piscicida), Streptococcus iniae (S. iniae), and red sea bream iridovirus (RSIV). As a result, it could be confirmed that lumican has a function of repairing tissue damage and immune response in red sea bream.