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Cited 2 time in webofscience Cited 3 time in scopus
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Differences in seroprevalence between epicenter and non-epicenter areas of the COVID-19 outbreak in South Koreaopen access

Authors
Jeong, Hye WonChang, Hyun-HaKim, Eun JiKim, Yu KyungKim, Se-MiKim, Eun-HaKim, Young-IlCasel, Mark Anthony B.Kim, Seong-GyuRollon, RareJang, Seung-GyuYu, Kwang-MinKim, Hee-SungPark, Hee SuePark, Su-JinKim, Yong-DaeKim, Eung-GookChoi, Young Ki
Issue Date
May-2021
Publisher
MICROBIOLOGICAL SOCIETY KOREA
Keywords
SARS-CoV-2; COVID-19; epicenter; seroprevalence; South Korea
Citation
JOURNAL OF MICROBIOLOGY, v.59, no.5, pp 530 - 533
Pages
4
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF MICROBIOLOGY
Volume
59
Number
5
Start Page
530
End Page
533
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/3801
DOI
10.1007/s12275-021-1095-7
ISSN
1225-8873
1976-3794
Abstract
To compare the standardized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence of high epicenter region with non-epicenter region, serological studies were performed with a total of 3,268 sera from Daegu City and 3,981 sera from Chungbuk Province. Indirect immunofluorescence assay (IFA) for SARS-CoV-2 IgG results showed a high seroprevalence rate in the Daegu City (epicenter) compared with a non-epicenter area (Chungbuk Province) (1.27% vs. 0.91%, P = 0.0358). It is noteworthy that the highest seroprevalence in Daegu City was found in elderly patients (70's) whereas young adult patients (20's) in Chungbuk Province showed the highest seroprevalence. Neutralizing antibody (NAb) titers were found in three samples from Daegu City (3/3, 268, 0.09%) while none of the samples from Chungbuk Province were NAb positive. These results demonstrated that even following the large outbreak, the seropositive rate of SARS-CoV-2 in the general population remained low in South Korea.
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