Detailed Information
Cited 4 time in 
Cited 5 time in 
Cited 5 time in
Metadata Downloads
Functional insights gained from structural analyses of DNA duplexes that contain UV-damaged photoproducts
- Authors
- Park, Chin-Ju; Lee, Joon-Hwa; Choi, Byong-Seok
- Issue Date
- Jan-2007
- Publisher
- AMER SOC PHOTOBIOLOGY
- Citation
- PHOTOCHEMISTRY AND PHOTOBIOLOGY, v.83, no.1, pp 187 - 195
- Pages
- 9
- Indexed
- SCIE
SCOPUS
- Journal Title
- PHOTOCHEMISTRY AND PHOTOBIOLOGY
- Volume
- 83
- Number
- 1
- Start Page
- 187
- End Page
- 195
- ISSN
- 0031-8655
1751-1097
- Abstract
- Ultraviolet photolesions endow DNA with distinct structural and dynamic properties. Biophysical studies of photoproduct-containing DNA have shown that these lesions affect the mutagenic properties of DNA and damage recognition by DNA repair systems. Recently obtained high-resolution cocrystal structures of damaged DNA bound to either DNA polymerase or DNA repair enzymes have enriched our understanding of the mechanisms by which DNA lesions are bypassed or recognized by DNA metabolizing proteins. Here, we summarize the results of these structural studies and discuss their implications for DNA metabolism.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 자연과학대학 > 화학과 > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.