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Cited 23 time in webofscience Cited 24 time in scopus
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Rituximab-CHOP induced interstitial pneumonitis in patients with disseminated extranodal marginal zone B cell lymphoma

Authors
Kim, Kwang MinKim, Ho-CheolJeon, Kyung-NyeoKim, Hoon-GuKang, Jung HunHahm, Jong RyealLee, Gyeong-Won
Issue Date
Feb-2008
Publisher
연세대학교의과대학
Keywords
interstitial pneumonitis; rituximab; lymphoma
Citation
Yonsei Medical Journal, v.49, no.1, pp 155 - 158
Pages
4
Indexed
SCIE
SCOPUS
KCI
Journal Title
Yonsei Medical Journal
Volume
49
Number
1
Start Page
155
End Page
158
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/27486
DOI
10.3349/ymj.2008.49.1.155
ISSN
0513-5796
1976-2437
Abstract
A 69-year-old male was diagnosed in February 2004 with stage IV extranodal marginal zone B cell lymphoma involving the mediastinal nodes, lung parenchyma and bone marrow with high LDH. Shortness of breath developed following the 5th course of Rituximab-CHOP chemotherapy (cyclophosphamide, Vincristine, Doxorubicin, Prednisolone). Bronchoscopy guided transbronchial lung biopsy revealed interstitial thickening and type II pneumocyte activation, compatible with interstitial pneumonitis. After treatment with prednisolone a complete resolution of the dyspnea was observed. The patient was well on routine follow-up at the outpatient clinic, with no progression of lymphoma or interstitial pneumonitis.
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