Pro- and anti-inflammatory cytokine expression and histopathological characteristics in canine brain with traumatic brain injury
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yu, Chi-Ho | - |
dc.contributor.author | Yhee, Ji-Young | - |
dc.contributor.author | Kim, Jong-Hyuk | - |
dc.contributor.author | Im, Keum-Soon | - |
dc.contributor.author | Kim, Na-Hyun | - |
dc.contributor.author | Jung, Dong-In | - |
dc.contributor.author | Lee, Hee-Chun | - |
dc.contributor.author | Chon, Seung-Ki | - |
dc.contributor.author | Sur, Jung-Hyang | - |
dc.date.accessioned | 2022-12-27T02:54:33Z | - |
dc.date.available | 2022-12-27T02:54:33Z | - |
dc.date.created | 2022-12-13 | - |
dc.date.issued | 2011-09 | - |
dc.identifier.issn | 1229-845X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gnu/handle/sw.gnu/23582 | - |
dc.description.abstract | We analyzed the expression level and cellular localization of pro- and anti-inflammatory cytokines and histopathologically characterized canine traumatic brain injury (TBI). Canine TBI brains revealed subarachnoid and cerebral cortical hemorrhage, neutrophilic infiltration, neuronal necrosis, astrocytosis, and vasogenic edema. Immunohistochemical evaluations suggested that both pro-inflammatory cytokines [interleukin (IL)-1 beta, IL-6, and tumor necrosis factor-alpha] and anti-inflammatory cytokines [IL-10 and transforming growth factor-beta (TGF-beta)] were highly expressed in neurons and neutrophils. In particular, the highest magnitude of expression was identified for IL-1 beta and TGF-beta. This data helps describe the pathologic characteristics of canine TBI, and may help in the design of potential therapeutic approaches to control secondary damage by inflammatory cytokines. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC VETERINARY SCIENCE | - |
dc.subject | DOG | - |
dc.subject | HYPOTHERMIA | - |
dc.subject | RAT | - |
dc.title | Pro- and anti-inflammatory cytokine expression and histopathological characteristics in canine brain with traumatic brain injury | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Dong-In | - |
dc.contributor.affiliatedAuthor | Lee, Hee-Chun | - |
dc.identifier.doi | 10.4142/jvs.2011.12.3.299 | - |
dc.identifier.scopusid | 2-s2.0-80052100562 | - |
dc.identifier.wosid | 000295017500016 | - |
dc.identifier.bibliographicCitation | JOURNAL OF VETERINARY SCIENCE, v.12, no.3, pp.299 - 301 | - |
dc.relation.isPartOf | JOURNAL OF VETERINARY SCIENCE | - |
dc.citation.title | JOURNAL OF VETERINARY SCIENCE | - |
dc.citation.volume | 12 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 299 | - |
dc.citation.endPage | 301 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001588722 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Veterinary Sciences | - |
dc.relation.journalWebOfScienceCategory | Veterinary Sciences | - |
dc.subject.keywordPlus | DOG | - |
dc.subject.keywordPlus | HYPOTHERMIA | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordAuthor | interleukin-1 | - |
dc.subject.keywordAuthor | interleukin-6 | - |
dc.subject.keywordAuthor | transforming growth factor-beta | - |
dc.subject.keywordAuthor | traumatic brain injury | - |
dc.subject.keywordAuthor | tumor necrosis factor-alpha | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Gyeongsang National University Central Library, 501, Jinju-daero, Jinju-si, Gyeongsangnam-do, 52828, Republic of Korea+82-55-772-0533
COPYRIGHT 2022 GYEONGSANG NATIONAL UNIVERSITY LIBRARY. ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.