갑상선에 발생한 원발성 림프종 1예

Abstract

We present a case of a 53-year-old woman with a rapidly growing neck mass. She had one-year history of hypothyroidism associatied with Hashimoto thyroiditis. She had noticed progressive dyspnea with rapid enlargement of the thyroid gland over a month. An incisional biopsy of the thyroid gland for combined pathology and immunohistochemistry revealed diffuse large B cell non-Hodgkin’s lymphoma. A combined chemotherapy including cyclophosphamide, doxorubicin, vincristine, prednisone plus rituximab (R-CHOP) was initiated, which dramatically shrunk the tumor and completely resolved the compression symptoms within a few days. Here we report on a case of thyroid lymphoma with a review of the relevant literature.