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NMR Study of Consensus DNA-binding Site for Arabidopsisthaliana ClassI Transcription Factor AtTCP1NMR Study of Consensus DNA-binding Site for Arabidopsisthaliana ClassI Transcription Factor AtTCP1

Other Titles
NMR Study of Consensus DNA-binding Site for Arabidopsisthaliana ClassI Transcription Factor AtTCP1
Authors
최용근이준화
Issue Date
2013
Publisher
한국자기공명학회
Keywords
NMR; DNA binding; Hydrogen exchange; TCP transcription factor
Citation
Journal of the Korean Magnetic Resonance Society, v.17, no.2, pp 76 - 80
Pages
5
Indexed
KCI
Journal Title
Journal of the Korean Magnetic Resonance Society
Volume
17
Number
2
Start Page
76
End Page
80
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/21166
ISSN
1226-6531
Abstract
The TCP domain is a DNA-binding domain present in plant transcription factors and has a similar structural feature to the bHTH motif of eukaryotic transcription factors. The imino proton exchange study has been performed for the DNA duplex containing the consensus DNA-binding site for the AtTCP11 transcription factor. The first two base pairs in the consensus 5'-GTGGG-3' sequence are relatively very unstable but lead to greater stabilization of the neighboring two G•C base pairs. These unique dynamic features of the five base pairs in the consensus DNA sequence might play crucial roles in the effective DNA binding of the AtTCP11 protein.
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자연과학대학 > 화학과 > Journal Articles

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