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Transient thyrotoxicosis from thyroiditis induced by sibutramine overdose: A case report
- Authors
- Kim, S. K.; Lee, S. M.; Yoo, S. S.; Hahm, J. R.; Jung, J. H.; Kim, H. S.; Kim, S.; Chung, S. I.; Jung, T. S.
- Issue Date
- Aug-2013
- Publisher
- SAGE PUBLICATIONS LTD
- Keywords
- Serotonin syndrome; sibutramine; thyroiditis; thyrotoxicosis
- Citation
- HUMAN & EXPERIMENTAL TOXICOLOGY, v.32, no.8, pp 890 - 892
- Pages
- 3
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- HUMAN & EXPERIMENTAL TOXICOLOGY
- Volume
- 32
- Number
- 8
- Start Page
- 890
- End Page
- 892
- ISSN
- 0960-3271
1477-0903
- Abstract
- Sibutramine is an antiobesity drug that inhibits the reuptake of serotonin and noradrenalin in the hypothalamus. A 37-year-old Korean man presented to the emergency room for the oral intake of 280mg of sibutramine. The patient was in thyrotoxic state. The (99m)Technetium-pertechnetate thyroid scan showed irregular uptake of radioisotope and thyroid-stimulating hormone receptor antibody and thyroperoxidase antibody were negative. Thyroid function normalized after that. The patient had transient thyrotoxicosis with thyroiditis. We report a case of thyrotoxicosis accompanied by thyroiditis resulting from the intentional overdose of sibutramine.
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