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Characterization and Anti-inflammatory Effects of Iodinated Acetylenic Acids Isolated from the Marine Sponges Suberites mammilaris and Suberites japonicus

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dc.contributor.authorHwang, Buyng Su-
dc.contributor.authorLee, Kyung-
dc.contributor.authorYang, Cao-
dc.contributor.authorJeong, Eun Ju-
dc.contributor.authorRho, Jung-Rae-
dc.date.accessioned2022-12-27T00:17:28Z-
dc.date.available2022-12-27T00:17:28Z-
dc.date.issued2013-12-
dc.identifier.issn0163-3864-
dc.identifier.issn1520-6025-
dc.identifier.urihttps://scholarworks.gnu.ac.kr/handle/sw.gnu/20307-
dc.description.abstractThe previously unknown compounds 1-4, acetylenic acids with one or two iodine atom(s), were isolated from the marine sponges Suberites mammilaris and Suberites japonicus. Their complete structures were determined using NMR and mass spectrometry. The methylated compounds la and 2a exhibited a strong NO inhibitory effect on RAW264.7 cells, while methylated 3a and 4a were inactive in RAW264.7 cells, but highly active in BV2 microglia cells.-
dc.format.extent5-
dc.language영어-
dc.language.isoENG-
dc.publisherAMER CHEMICAL SOC-
dc.titleCharacterization and Anti-inflammatory Effects of Iodinated Acetylenic Acids Isolated from the Marine Sponges Suberites mammilaris and Suberites japonicus-
dc.typeArticle-
dc.publisher.location미국-
dc.identifier.doi10.1021/np400793r-
dc.identifier.scopusid2-s2.0-84891409828-
dc.identifier.wosid000329331200025-
dc.identifier.bibliographicCitationJOURNAL OF NATURAL PRODUCTS, v.76, no.12, pp 2355 - 2359-
dc.citation.titleJOURNAL OF NATURAL PRODUCTS-
dc.citation.volume76-
dc.citation.number12-
dc.citation.startPage2355-
dc.citation.endPage2359-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaPlant Sciences-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalWebOfScienceCategoryPlant Sciences-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.subject.keywordPlusPOLYACETYLENES-
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자연과학대학 > 항노화신소재과학과 > Journal Articles

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자연과학대학 (항노화신소재과학과)
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