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Synthetic Biology and Metabolic Engineering for Marine Carotenoids: New Opportunities and Future Prospects
- Authors
- Wang, Chonglong; Kim, Jung-Hun; Kim, Seon-Won
- Issue Date
- Sep-2014
- Publisher
- Multidisciplinary Digital Publishing Institute (MDPI)
- Keywords
- marine carotenoids; carotenoid synthesis; carotenoid modification; metabolic engineering; synthetic biology; protein engineering
- Citation
- Marine Drugs, v.12, no.9, pp 4810 - 4832
- Pages
- 23
- Indexed
- SCIE
SCOPUS
- Journal Title
- Marine Drugs
- Volume
- 12
- Number
- 9
- Start Page
- 4810
- End Page
- 4832
- ISSN
- 1660-3397
1660-3397
- Abstract
- Carotenoids are a class of diverse pigments with important biological roles such as light capture and antioxidative activities. Many novel carotenoids have been isolated from marine organisms to date and have shown various utilizations as nutraceuticals and pharmaceuticals. In this review, we summarize the pathways and enzymes of carotenoid synthesis and discuss various modifications of marine carotenoids. The advances in metabolic engineering and synthetic biology for carotenoid production are also reviewed, in hopes that this review will promote the exploration of marine carotenoid for their utilizations.
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