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Cited 2 time in webofscience Cited 3 time in scopus
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Development of an Advanced Synthetic Route to Macrosphelides and Its Application to the Discovery of a More Potent Macrosphelide Derivative

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dc.contributor.authorHeo, Yu Mi-
dc.contributor.authorLee, Hunseok-
dc.contributor.authorShin, Young Kee-
dc.contributor.authorPaek, Seung-Mann-
dc.date.accessioned2022-12-26T22:52:05Z-
dc.date.available2022-12-26T22:52:05Z-
dc.date.issued2014-10-
dc.identifier.issn1420-3049-
dc.identifier.urihttps://scholarworks.gnu.ac.kr/handle/sw.gnu/18745-
dc.description.abstractThe discovery of a more cytotoxic macrosphelide derivative, including its total synthesis and bioassay are described. Application of the Koide protocol to a readily available propagylic alcohol allowed the rapid and practical synthesis of a macrosphelide A skeleton. This strategy enabled the successful improvement of the cytotoxic activity of the macrosphelide derivative.-
dc.format.extent12-
dc.language영어-
dc.language.isoENG-
dc.publisherMDPI-
dc.titleDevelopment of an Advanced Synthetic Route to Macrosphelides and Its Application to the Discovery of a More Potent Macrosphelide Derivative-
dc.typeArticle-
dc.publisher.location스위스-
dc.identifier.doi10.3390/molecules191015572-
dc.identifier.scopusid2-s2.0-84907482374-
dc.identifier.wosid000344456100013-
dc.identifier.bibliographicCitationMOLECULES, v.19, no.10, pp 15572 - 15583-
dc.citation.titleMOLECULES-
dc.citation.volume19-
dc.citation.number10-
dc.citation.startPage15572-
dc.citation.endPage15583-
dc.type.docTypeArticle-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusTHIAZOLE SIDE-CHAIN-
dc.subject.keywordPlusCELL-CELL ADHESION-
dc.subject.keywordPlusNATURAL-PRODUCTS-
dc.subject.keywordPlusARTIFICIAL MACROSPHELIDES-
dc.subject.keywordPlusDRUG DISCOVERY-
dc.subject.keywordPlusSEA HARE-
dc.subject.keywordPlusAPOPTOSIS-
dc.subject.keywordPlus(+)-MACROSPHELIDE-B-
dc.subject.keywordPlusINHIBITORS-
dc.subject.keywordPlusLIBRARY-
dc.subject.keywordAuthormacrosphelides-
dc.subject.keywordAuthornatural product-
dc.subject.keywordAuthortotal synthesis-
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