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Cited 26 time in webofscience Cited 30 time in scopus
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Expression of neurotrophic factors in injured spinal cord after transplantation of human-umbilical cord blood stem cells in rats

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dc.contributor.authorChung, Hyo-jin-
dc.contributor.authorChung, Wook-hun-
dc.contributor.authorLee, Jae-Hoon-
dc.contributor.authorChung, Dai-Jung-
dc.contributor.authorYang, Wo-Jong-
dc.contributor.authorLee, A-Jin-
dc.contributor.authorChoi, Chi-Bong-
dc.contributor.authorChang, Hwa-Seok-
dc.contributor.authorKim, Dae-Hyun-
dc.contributor.authorSuh, Hyun Jung-
dc.contributor.authorLee, Dong-Hun-
dc.contributor.authorHwang, Soo-Han-
dc.contributor.authorDo, Sun Hee-
dc.contributor.authorKim, Hwi-Yool-
dc.date.accessioned2022-12-26T20:19:49Z-
dc.date.available2022-12-26T20:19:49Z-
dc.date.issued2016-03-
dc.identifier.issn1229-845X-
dc.identifier.issn1976-555X-
dc.identifier.urihttps://scholarworks.gnu.ac.kr/handle/sw.gnu/15644-
dc.description.abstractWe induced percutaneous spinal cord injuries (SCI) using a balloon catheter in 45 rats and transplanted human umbilical cord blood derived mesenchymal stem cells (hUCB-MSCs) at the injury site. Locomotor function was significantly improved in hUCB-MSCs transplanted groups. Quantitative ELISA of extract from entire injured spinal cord showed increased expression of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and neurotrophin-3 (NT-3). Our results show that treatment of SCI with hUCB-MSCs can improve locomotor functions, and suggest that increased levels of BDNF, NGF and NT-3 in the injured spinal cord were the main therapeutic effect.-
dc.format.extent6-
dc.language영어-
dc.language.isoENG-
dc.publisherKOREAN SOC VETERINARY SCIENCE-
dc.titleExpression of neurotrophic factors in injured spinal cord after transplantation of human-umbilical cord blood stem cells in rats-
dc.typeArticle-
dc.publisher.location대한민국-
dc.identifier.doi10.4142/jvs.2016.17.1.97-
dc.identifier.scopusid2-s2.0-84962757941-
dc.identifier.wosid000373246900012-
dc.identifier.bibliographicCitationJOURNAL OF VETERINARY SCIENCE, v.17, no.1, pp 97 - 102-
dc.citation.titleJOURNAL OF VETERINARY SCIENCE-
dc.citation.volume17-
dc.citation.number1-
dc.citation.startPage97-
dc.citation.endPage102-
dc.type.docTypeArticle-
dc.identifier.kciidART002090570-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaVeterinary Sciences-
dc.relation.journalWebOfScienceCategoryVeterinary Sciences-
dc.subject.keywordPlusMARROW STROMAL CELLS-
dc.subject.keywordPlusFUNCTIONAL RECOVERY-
dc.subject.keywordPlusBRAIN-
dc.subject.keywordPlusPATHOPHYSIOLOGY-
dc.subject.keywordPlusREMYELINATE-
dc.subject.keywordPlusMODEL-
dc.subject.keywordPlusBDNF-
dc.subject.keywordAuthorbrain-derived neurotrophic factor-
dc.subject.keywordAuthornerve growth factor-
dc.subject.keywordAuthorneurotrophic factor-
dc.subject.keywordAuthorneurotrophin-3-
dc.subject.keywordAuthorspinal cord injury-
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