The Correlation between Body Mass Index and Routine Parameters in Men Over Fifty

Abstract

Purpose: This study aimed to investigate the relationships between body mass index (BMI) and prostate- specific antigen (PSA) levels, international prostate symptom score (IPSS), quality of life (QoL), and prostate volume (PV). Materials and Methods: Height, weight, PSA levels, PV, and IPSS were analyzed in 15,435 patients who underwent a prostate examination between 2001 and 2014. Patients aged < 50 years or with a PSA level >= 10 ng/mL were excluded. The relationships between BMI and PSA, IPSS, QoL, and PV were analyzed by a scatter plot, one-way analysis of variance, and the Pearson correlation coefficient. Results: The mean age was 71.95 +/- 7.63 years, the mean BMI was 23.59 +/- 3.08 kg/m(2), the mean PSA level was 1.45 +/- 1.45 ng/mL, the mean IPSS was 15.53 +/- 8.31, the mean QoL score was 3.48 +/- 1.25, and the mean PV was 29.72 +/- 14.02 mL. PSA, IPSS, and QoL showed a tendency to decrease with increasing BMI, and there were statistically significant differences for each parameter (p <= 0.001). PV showed a significant tendency to increase with BMI (p<0.001). In the correlation analysis, BMI showed a statistically significant correlation (p<0.001) with PSA, IPSS, and QoL, although the correlations were very weak. In contrast, BMI showed a significant correlation with PV (p<0.001), with a meaningful Pearson correlation coefficient of 0.124. Conclusions: Higher BMI was associated with lower PSA levels and higher IPSS and QoL scores. Meanwhile, PV increased with BMI. Although obese individuals had a greater PV, obesity did not aggravate lower urinary tract symptoms.