Feline APOBEC3s, Barriers to Cross-Species Transmission of FIV?
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zhang, Zeli | - |
dc.contributor.author | Gu, Qinyong | - |
dc.contributor.author | Marino, Daniela | - |
dc.contributor.author | Lee, Kyeong-Lim | - |
dc.contributor.author | Kong, Il-Keun | - |
dc.contributor.author | Haeussinger, Dieter | - |
dc.contributor.author | Muenk, Carsten | - |
dc.date.accessioned | 2022-12-26T17:03:54Z | - |
dc.date.available | 2022-12-26T17:03:54Z | - |
dc.date.created | 2022-12-13 | - |
dc.date.issued | 2018-04 | - |
dc.identifier.issn | 1999-4915 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gnu/handle/sw.gnu/11757 | - |
dc.description.abstract | The replication of lentiviruses highly depends on host cellular factors, which defines their species-specific tropism. Cellular restriction factors that can inhibit lentiviral replication were recently identified. Feline immunodeficiency virus (FMV) was found to be sensitive to several feline cellular restriction factors, such as apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3 (APOBEC3) and tetherin, but FIV evolved to counteract them. Here, we describe the molecular mechanisms by which feline APOBEC3 restriction factors inhibit FIV replication and discuss the molecular interaction of APOBEC3 proteins with the viral antagonizing protein Vif. We speculate that feline APOBEC3 proteins could explain some of the observed FIV cross-species transmissions described in wild Felids. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.subject | IMMUNODEFICIENCY VIRUS VIF | - |
dc.subject | HIV-1 REVERSE TRANSCRIPTION | - |
dc.subject | PROTEINS REGULATE AUTOPHAGY | - |
dc.subject | AMINO-ACID-RESIDUES | - |
dc.subject | CD4(+) T-CELLS | - |
dc.subject | LENTIVIRAL VIF | - |
dc.subject | DOMESTIC CATS | - |
dc.subject | ANTIRETROVIRAL ACTIVITY | - |
dc.subject | RESTRICTION FACTORS | - |
dc.subject | LEUKEMIA-VIRUS | - |
dc.title | Feline APOBEC3s, Barriers to Cross-Species Transmission of FIV? | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kong, Il-Keun | - |
dc.identifier.doi | 10.3390/v10040186 | - |
dc.identifier.scopusid | 2-s2.0-85045338352 | - |
dc.identifier.wosid | 000435184400047 | - |
dc.identifier.bibliographicCitation | VIRUSES-BASEL, v.10, no.4 | - |
dc.relation.isPartOf | VIRUSES-BASEL | - |
dc.citation.title | VIRUSES-BASEL | - |
dc.citation.volume | 10 | - |
dc.citation.number | 4 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Virology | - |
dc.relation.journalWebOfScienceCategory | Virology | - |
dc.subject.keywordPlus | IMMUNODEFICIENCY VIRUS VIF | - |
dc.subject.keywordPlus | HIV-1 REVERSE TRANSCRIPTION | - |
dc.subject.keywordPlus | PROTEINS REGULATE AUTOPHAGY | - |
dc.subject.keywordPlus | AMINO-ACID-RESIDUES | - |
dc.subject.keywordPlus | CD4(+) T-CELLS | - |
dc.subject.keywordPlus | LENTIVIRAL VIF | - |
dc.subject.keywordPlus | DOMESTIC CATS | - |
dc.subject.keywordPlus | ANTIRETROVIRAL ACTIVITY | - |
dc.subject.keywordPlus | RESTRICTION FACTORS | - |
dc.subject.keywordPlus | LEUKEMIA-VIRUS | - |
dc.subject.keywordAuthor | FIV | - |
dc.subject.keywordAuthor | restriction factors | - |
dc.subject.keywordAuthor | feline APOBEC3 | - |
dc.subject.keywordAuthor | cross-species transmission | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Gyeongsang National University Central Library, 501, Jinju-daero, Jinju-si, Gyeongsangnam-do, 52828, Republic of Korea+82-55-772-0533
COPYRIGHT 2022 GYEONGSANG NATIONAL UNIVERSITY LIBRARY. ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.