Effect of Volatile Organic Chemicals in Chrysanthemum indicum Linne on Blood Pressure and Electroencephalogram

Abstract

This study identified the volatile organic compounds in the essential oils that are extracted from Chrysanthemum indicum Linne (C. indicum Linne) and investigated the effects of the inhalation of these compounds. We detected a total of 41 volatile organic compounds, including 32 hydrocarbons, four acids, three alcohols, two ketones, and one aldehyde. In a sniffing test, seven types of volatile organic compounds were identified. Furthermore, the volatile organic compounds in C. indicum Linne that were identified were found to be derived from 1,8-cineole and camphor. After inhalation of the essential oils, the subjects' systolic blood pressure and heart rate decreased. This indicates that inhalation of the essential oils extracted from C. indicum Linne provides mental and physical relaxation. We examined the changes in electroencephalogram findings that are observed after C. indicum Linne essential oil inhalation. An increase in theta and alpha waves, which usually appear during relaxation, as well as a decrease in beta and gamma waves, which appear during brain activity such as excessive attention, were noted. These results indicate that C. indicum Linne essential oil inhalation helps to reduce blood pressure and may provide mental and physical relaxation.