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SCIESCOPUS
Heme oxygenase-1 induction by (S)-enantiomer of YS-51 (YS-5 1S), a synthetic isoquinoline alkaloid, inhibits nitric oxide production and nuclear factor-kappa B translocation in ROS 17/2.8 cells activated with inflammatory stimulants

Chaea, Han-Jung; Kim, Hyung-Ryong; Kang, Young Jin; Hyun, Kwang Chul; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Yun-Choi, Hye Sook; Chang, Ki Churl

ArticleIssue Date2007CitationINTERNATIONAL IMMUNOPHARMACOLOGY, v.7, no.12, pp 1559 - 1568PublisherELSEVIER SCIENCE BV
SCIESCOPUS
HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride

Tsoyi, Konstantin; Kim, Hye Jung; Shin, Jae-Soo; Kim, Dal-Hyun; Cho, Hee-Jeong; Lee, Sung Sook; Ahn, Sun Kil; Yun-Choi, Hye Sook; Lee, Jae Heun; Seo, Han Geuk, et al.

ArticleIssue Date2008CitationCELLULAR SIGNALLING, v.20, no.10, pp 1839 - 1847PublisherELSEVIER SCIENCE INC
SCIESCOPUS
Regulation of lipopolysaccharide-induced inducible nitric-oxide synthase expression through the nuclear factor-kappa B pathway and interferon-beta/tyrosine kinase 2/Janus tyrosine kinase 2-signal transducer and activator of transcription-1 signaling cascades by 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid

Kim, Hye Jung; Tsoyi, Konstantin; Heo, Ja Myung; Kang, Young Jin; Park, Min Kyu; Lee, Young Soo; Lee, Jae Heun; Seo, Han Geuk; Yun-Choi, Hye Sook; Chang, Ki Churl

ArticleIssue Date2007CitationJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, v.320, no.2, pp 782 - 789PublisherAMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
SCIESCOPUS
(S)-1-(alpha-Naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolin e (CKD712) Reduces Rat Myocardial Apoptosis against Ischemia and Reperfusion Injury by Activation of Phosphatidylinositol 3-Kinase/Akt Signaling and Anti-inflammatory Action in Vivo

Jin, Yong Chun; Lee, Young Soo; Kim, Young Min; Seo, Han Geuk; Lee, Jae Heun; Kim, Hye Jung; Yun-Choi, Hye Sook; Chang, Ki Churl

ArticleIssue Date2009CitationJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, v.330, no.2, pp 440 - 448PublisherAMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
SCIESCOPUS
Upregulation of PTEN by CKD712, a synthetic tetrahydroisoquinoline alkaloid, selectively inhibits lipopolysaccharide-induced VCAM-1 but not ICAM-1 expression in human endothelial cells

Tsoyi, Konstantin; Kim, Woo Sang; Kim, Young Min; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Yun-Choi, Hye Sook; Chang, Ki Churl

ArticleIssue Date2009CitationATHEROSCLEROSIS, v.207, no.2, pp 412 - 419PublisherELSEVIER IRELAND LTD
SCIESCOPUS
YS 49, 1-(alpha-naphtylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, regulates angiotensin II-stimulated ROS production, JNK phosphorylation and vascular smooth muscle cell proliferation via the induction of heme oxygenase-1

Sun, Jin Ji; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Yun-Choi, Hye Sook; Chang, Ki Churl

ArticleIssue Date2008CitationLIFE SCIENCES, v.82, no.11-12, pp 600 - 607PublisherPERGAMON-ELSEVIER SCIENCE LTD
SCIESCOPUS
YS 51,1-(beta-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,-tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1

Heo, Ja Myung; Kim, Hye Jung; Ha, Yu Mi; Park, Min Kyu; Kang, Young Jin; Lee, Young Soo; Seo, Han Geuk; Lee, Jae Heun; Yun-Choi, Hye Sook; Chang, Ki Churl

ArticleIssue Date2007CitationBIOCHEMICAL PHARMACOLOGY, v.74, no.9, pp 1361 - 1370PublisherPERGAMON-ELSEVIER SCIENCE LTD
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